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  • The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence in accordance with a news release by them on 10-12-2010.

    Using two separate drugs to shed pounds can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you should err assisting caution and permit the FDA do its job and demand some research be done so that the public recognizes the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies will be in business to generate income and that they would say anything to keep people on their medications.

    Researchers found that participants using this drug for a year, dropped a few pounds within four weeks and have kept the body weight off through the 56 weeks from the study. Contrave is a combination of the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which might be made up of many active ingredient, which can make them more potent and safer.

    Combo-pilling will be the newest fad or better yet the newest ahead under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills has become popular could be the fact that since right now there are no long term prescription slimming capsules that have been authorized by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be authorized by the FDA.

    Seizures can be a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug may also raise blood pressure levels and heartbeat, and shouldn't be used in people who have a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure level and heartbeat and must 't be used in patients with uncontrolled high hypertension, in addition to by a person with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients with a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients on the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.

    Suboxone includes two drugs; buprenorphine and naloxone. The naloxone is irrelevant if the addict uses the medication properly, but in the event the tablet is dissolved in water and injected the naloxone may cause instant withdrawal. When suboxone is employed correctly, the naloxone is destroyed inside liver after that uptake from your intestines and has no therapeutic effect. Buprenorphine is the active substance; it can be absorbed within the tongue (and through the mouth) but destroyed by the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I used this formulation when the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I have treated addicts who may have had gastric bypass, the location where the first area of the intestine is bypassed and also the stomach contents empty right into a more distal section of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the task with normal anatomy in which the drug is taken up with the duodenum and transferred directly to the liver from the portal vein, where it is quickly and completely destroyed. After gastric bypass naloxone can be taken on by areas of the intestine that are not served from the portal system, causing blood degrees of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.